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Erection Cocktail: Best Drink for Erectile Dysfunction

June 08, 2022 - Admin
category: Energy, Health, Muscle Growth, Sex Cock-Tail, Strength

 

Quality, purity, and potency are crucial in both pharmaceutical and nutraceutical applications. Unfortunately, not every company prioritizes the consumer's best interests.

Although many companies aim to serve consumers well while making a profit, some do not deliver as advertised. Over the years, the number of substandard and falsified products has increased in both the pharmaceutical and dietary supplement industries. A World Health Organization study in 2017 found that about 10% of medicines in developing countries were falsified or substandard.

Male enhancement products are often incorrectly dosed. A common adulterant in sexual enhancement supplements is sildenafil, commonly known as Viagra.

Research published in the Journal of the American Medical Association in 2018 found that of 353 male enhancement supplements tested, 166 were spiked with sildenafil.

Recent research in the International Journal of Pharmaceuticals found that products claiming to be "natural" or "herbal" remedies for male enhancement often contained sildenafil.

Alarmingly, some of these products contained ~200 mg sildenafil citrate, double the maximum recommended daily dose of 100 mg. While higher doses are sometimes used when 100 mg is ineffective, 63% of men taking 150-200 mg experienced adverse reactions such as headaches, facial flushing, visual disturbances, and gastrointestinal distress.

Given these concerns, it may seem better to obtain the actual pharmaceutical. However, sildenafil is also one of the most commonly falsified pharmaceuticals globally.

Considering these challenges, evaluating all options is wise. A precisely formulated erection cocktail might be the best path to male enhancement, combining ingredients that support and fuel male performance from multiple fronts.

We have researched and gathered the most beneficial supplements for natural male enhancement in AML SEX COCKTAIL. This erection cocktail is an amino acid that converts to L-Arginine, the primary "fuel" for nitric oxide production, making it one of the best drinks for erectile dysfunction.

L-Citrulline

L-Citrulline is more efficiently converted to L-arginine than regular L-arginine and causes less gastrointestinal distress at higher doses. It offers greater increases in nitric oxide production, which is crucial because nitric oxide is the key molecule responsible for relaxing penile smooth muscle. Nitric oxide also increases vasodilation and blood flow to all body regions.

What's more, L-Citrulline is more efficiently converted to L-arginine than regular L-arginine (and comes with considerably less GI distress at higher doses), and, thus, offers greater increases in nitric oxide production.

The reason this is important is that nitric oxide is recognized as the key molecule responsible for relaxation of penile smooth muscle. FYI, nitric oxide also increases vasodilation and blood flow…to ALL regions of the body.†

Research has found that L-citrulline improves blood vessel flexibility and erectile function. Supplementation with L-arginine (6g/day for 3 months) significantly improved penile erectile function. Since L-citrulline is superior for increasing serum arginine levels and nitric oxide production, it is a better choice for those seeking male enhancement.

Newly published research found that supplementation with L-arginine (6g/day for 3 months) significantly improved penile erectile function.[10]†

Seeing as L-citrulline is a superior option for increasing serum arginine levels (and therefore NO production), it is clearly a better choice for those seeking male enhancement.†

AML Sex Cock-Tail provides a full 6,000 mg of L-Citrulline per serving, making it an effective cocktail for nitric oxide production. However, just as you can only fill a tank with so much gas before it overflows, the body can only use so much citrulline at one time. Adding more won't necessarily increase output.

Fortunately, other agents can further aid nitric oxide production and enhance its bioavailability, meaning the body uses it more efficiently without waste.

Polyphenols

Enhancing nitric oxide production can be accomplished in several different ways. The primary way is by elevating arginine concentrations in the blood (more "fuel" can thus be converted into nitric oxide).

However, just as you can only put so much gas in a tank before it starts to spill over, there's only so much citrulline the body can use at one time. Putting more in won't necessarily equal continually more output.

The good news is that there are other agents that can be utilized to further aid NO production and increase its bioavailability (meaning that it's more efficiently used by the body and not wasted).

One class of "supporting actors" in naturally enhancing nitric oxide production includes a diverse range of plant compounds. These compounds offer numerous health benefits, including increased nitric oxide production, blood glucose support, and cardiovascular health. Research indicates that men with the highest dietary polyphenol intake have a significantly lower incidence of erectile dysfunction. Some studies find that consuming just 50 mg/day of flavonoids reduces the risk of erectile dysfunction.

Polyphenols are a vast and diverse cast of plant compounds that are known to confer numerous beneficial health benefits, including increased NO production, blood glucose support, and cardiovascular support.†

It's also noteworthy that research finds that men with the highest dietary polyphenol intake have a significantly lower incidence of erectile dysfunction.[11,12] In fact, some studies find that consuming just 50 mg/day of flavonoids reduced the risk of erectile dysfunction by 32%.[13]†

AML Sex Cock-Tail contains three rich sources of polyphenols:

  • Beet Root Extract (500 mg)
  • Grape Skin Extract (100 mg)
  • Pine Bark Extract (80 mg)

 

Antioxidant Support

Oxidative stress occurs when there is an imbalance between reactive oxygen species (ROS) and the body's antioxidant defense systems. If unchecked, oxidative stress can lead to cell and tissue injury, resulting in vascular dysfunction. Increased oxidative stress can cause:

  • Vasoconstriction
  • Vascular remodeling
  • Inflammation
  • Fibrosis

 

Fortifying the body's antioxidant defense systems is essential for maintaining a healthy balance between ROS and antioxidants, thereby supporting overall health and wellness.

Two powerful antioxidant support supplements are:

  • N-acetylcysteine (NAC)
  • Vitamin C

NAC is a more bioavailable form of the amino acid L-cysteine, serving as a precursor to the body's "master antioxidant." Studies have shown NAC's benefits for immune support, cardiovascular health, organ health, and nitric oxide enhancement. NAC also enhances nitric oxide bioavailability and serves as a precursor for synthesizing hydrogen sulfide, a powerful vasodilator that increases healthy blood flow and enhances penile erection and sexual function. Animal studies have highlighted NAC's potential benefits in maintaining penile length and erectile function by reducing fibrosis.

Countless studies have been performed with NAC over the years and uncovered a number of benefits in regards to immune support, cardiovascular support, organ health, and nitric oxide production.†

NAC also enhances the bioavailability of nitric oxide in the body, and it serves as a precursor for the synthesis of hydrogen sulfide, which itself is a powerful vasodilator that increases healthy blood flow and enhances penile erection and sexual performance.[15,16]†

Recent animal studies have also highlighted some potential benefits of NAC in regards to maintaining penile length and erectile function by reducing fibrosis.[17]†

Vitamin C is a well-known antioxidant and free radical scavenger, commonly used to support immune function. In addition to its cold season benefits, vitamin C helps combat oxidative stress and supports nitric oxide production, benefiting healthy blood flow.

Added Folic Acid

Folic acid is a precursor of tetrahydrobiopterin (BH4), known to enhance nitric oxide bioavailability and systemic cGMP levels in healthy adults. cGMP is another important molecule involved in vasorelaxation and healthy blood flow.

High doses of folic acid have been found to support endothelial cells by reducing levels of homocysteine and increasing NO production.[18]

By combining folic acid with vitamin C and NAC, AML Sex Cock-Tail provides robust support for antioxidant defense, nitric oxide synthesis, and blood flow.

Sildenafil remains the most commonly used pharmaceutical for treating erectile dysfunction and male enhancement. It primarily works as a PDE-5 inhibitor, the enzyme that degrades cGMP and reduces blood flow in the corpus cavernosum. However, sildenafil is also one of the most commonly falsified products on the market.

Icariin, a natural plant constituent, also inhibits PDE-5. Combined with other pro-erectile ingredients in AML Sex Cock-Tail, it offers enhanced benefits. Previous research in the Journal Andrology compared sildenafil (50 mg) alone or with L-arginine (3,000 mg) daily for eight weeks, finding the combination more effective than sildenafil alone for erectile function. As mentioned earlier, L-citrulline is more effective than L-arginine for raising blood arginine levels. Therefore, a PDE-5 inhibitor combined with citrulline would be much more effective.

Advanced Molecular Labs SEX COCKTAILâ„¢ is the most scientifically advanced natural sexual enhancement supplement ever created!

For best results, drink this erection cocktail 30-60 minutes before bedtime daily to support healthy vasodilation, blood flow, and natural sexual function. These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

†These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

© Published by Advanced Research Media, Inc., 2022

© Reprinted with permission from Advanced Research Media, Inc.

References

  1. World Health Organization, 2017. A study on Public Health and Socio-economic Impact of Substandard and Falsified Medical Products.
  2. Tucker J, Fischer T, Upjohn L, Mazzera D, Kumar M. Unapproved Pharmaceutical Ingredients Included in Dietary Supplements Associated With US Food and Drug Administration Warnings [published correction appears in JAMA Netw Open. 2018 Nov 2;1(7):e185765]. JAMA Netw Open. 2018;1(6):e183337. Published 2018 Oct 5. doi:10.1001/jamanetworkopen.2018.3337
  3. Ho HMK, Xiong Z, Wong HY, Buanz A. The era of fake medicines: Investigating counterfeit medicinal products for erectile dysfunction disguised as herbal supplements. Int J Pharm. 2022 Apr 5;617:121592. doi: 10.1016/j.ijpharm.2022.121592. Epub 2022 Feb 16. PMID: 35182703.
  4. G. McMahon. High dose sildenafil citrate as a salvage therapy for severe erectile dysfunction. Int. J. Impot. Res., 14 (6) (2002), pp. 533-538, 10.1038/sj.ijir.3900936
  5. Yoshida, N.; Yuasa, M.; Sovannarith, T.; Dararth, E.; Keila, T.; Kiet, H.B.; Tsuboi, H.; Tanimoto, T.; Kimura, K. A Cross-Sectional Investigation for Verification of Globalization of Falsified Medicines in Cambodia, Indicated by Tablets of Sildenafil Citrate. Pharmacy 2019, 7, 111. https://doi.org/10.3390/pharmacy7030111
  6. Sweileh, W.M. Substandard and falsified medical products: bibliometric analysis and mapping of scientific research. Global Health 17, 114 (2021). https://doi.org/10.1186/s12992-021-00766-5
  7. Short-term effects of l-citrulline supplementation on arterial stiffness in middle-aged men. Ochiai, Masayuki et al. (March 2012) International Journal of Cardiology, Volume 155, Issue 2, 257-261 doi: 10.1016/j.ijcard.2010.10.004
  8. Luigi Cormio, Mario De Siati, Fabrizio Lorusso, Oscar Selvaggio, Lucia Mirabella, Francesca Sanguedolce, Giuseppe Carrieri. Oral L-Citrulline Supplementation Improves Erection Hardness in Men With Mild Erectile Dysfunction. January 2011. Urology. https://www.sciencedirect.com/science/article/pii/S0090429510016614
  9. Shirai M, Hiramatsu I, Aoki Y, et al. Oral L-citrulline and Transresveratrol Supplementation Improves Erectile Function in Men With Phosphodiesterase 5 Inhibitors: A Randomized, Double-Blind, Placebo-Controlled Crossover Pilot Study. Sex Med 2018;6(4):291-296. doi:10.1016/j.esxm.2018.07.001
  10. Menafra, D et al. "Long-term high-dose L-arginine supplementation in patients with vasculogenic erectile dysfunction: a multicentre, double-blind, randomized, placebo-controlled clinical trial." Journal of endocrinological investigation vol. 45,5 (2022): 941-961. doi:10.1007/s40618-021-01704-3
  11. Trebaticky B, Muchova J, Ziaran S, Bujdak P, Breza J, Durackova Z. Natural polyphenols improve erectile function and lipid profile in patients suffering from erectile dysfunction. Bratisl Lek Listy. 2019;120(12):941-944. doi: 10.4149/BLL_2019_158. PMID: 31855055.
  12. Cassidy A, Franz M, Rimm EB. Dietary flavonoid intake and incidence of erectile dysfunction. Am J Clin Nutr. 2016;103(2):534-541. doi:10.3945/ajcn.115.122010
  13. Russo GI, Broggi G, Cocci A, et al. Relationship between Dietary Patterns with Benign Prostatic Hyperplasia and Erectile Dysfunction: A Collaborative Review. Nutrients. 2021;13(11):4148. Published 2021 Nov 19. doi:10.3390/nu13114148
  14. Rodriguez-Porcel, M., Chade, A. R., and Miller, J. D. (2017). Studies on Atherosclerosis. Oxidative Stress in Applied Basic Research and Clinical Practice, 1st Edn. Berlin: Springer. doi: 10.1007/978-1-4899-7693-2
  15. Ezeriņa D, Takano Y, Hanaoka K, Urano Y, Dick TP. N-Acetyl Cysteine Functions as a Fast-Acting Antioxidant by Triggering Intracellular H2S and Sulfane Sulfur Production. Cell Chem Biol. 2018;25(4):447-459.e4. doi:10.1016/j.chembiol.2018.01.011
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  17. Ma M, Wu CJ, Zhang P, et al. N-acetylcysteine maintains penile length and erectile function in bilateral cavernous nerve crush rat model by reducing penile fibrosis. Asian J Androl. 2021;23(2):215-221. doi:10.4103/aja.aja_17_20
  18. Zhang, M., Wen, J., Wang, X., & Xiao, C. (2014). High-dose folic acid improves endothelial function by increasing tetrahydrobiopterin and decreasing homocysteine levels. Molecular Medicine Reports, 10, 1609-1613. https://doi.org/10.3892/mmr.2014.2332
  19. Corbin, J. Mechanisms of action of PDE5 inhibition in erectile dysfunction. Int J Impot Res 16, S4-S7 (2004). https://doi.org/10.1038/sj.ijir.3901205
  20. Feng Jin, Qi-Hai Gong, Ya-Sha Xu, Li-Na Wang, Hai Jin, Fei Li, Li-Sheng Li, Yue-Ming Ma, Jing-Shan Shi, Icariin, a phoshphodiesterase-5 inhibitor, improves learning and memory in APP/PS1 transgenic mice by stimulation of NO/cGMP signalling, International Journal of Neuropsychopharmacology, Volume 17, Issue 6, June 2014, Pages 871-881, https://doi.org/10.1017/S1461145713001533
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