AML TEST:

BEST NATURAL FREE TESTOSTERONE SUPPORT SUPPLEMENT!*

HELPS SUPPORT FREE TESTOSTERONE NATURALLY*

HELPS COMBAT CORTISOL*

Based on Latest Scientific Research*

TWO CAPSULES OF AML TEST PROVIDES:

1 DHEA (dehydroepiandrosterone) 50 mg

2 BORON 10 mg

3 FENUGREEK SEED EXTRACT (Trigonella Foenum-Graecum) 600 mg

4 TONGKAT ALI (Eurycoma Longifolia) 200 mg

5 RED WINE EXTRACT (Standardized for 30% Polyphenols.)*

6 VITAMIN D 3332/IUs

7 ZINC 30 mg

Directions: For best results, take two capsules of AML TEST with an evening meal, or one hour before morning high-intensity training (HIIT) and resistance training program. *

WHAT ALSO WORKS AND WHAT DOESN’T

(As part of a Diet and Resistance Exercise Training Program.)

D-Aspartic acid, Tribulus terrestris, stinging nettle, saw palmetto, maca root extract, damiana leaf extract, indole 3-carbinol and 3,3-diindolylmethane (DIM) are not present in AML TEST because of lack of published, scientific human research supporting increased free or total testosterone in humans.* Also, purified supplements of indole-3-carbinol and DIM are shown to be phytoestrogens, anti-androgens (blocking androgen receptors) and endocrine disruptors. They shouldn’t be taken as dietary supplements if you want to support testosterone function! If you want to get your health benefits from these compounds, then play it safe and eat your cruciferous vegetables such as broccoli, cauliflower, Brussels sprouts or asparagus.

For example, the latest research has shown that D-aspartic acid decreases testosterone! Australian scientists from the University of Western Sydney, led by Geoffrey Melville, found that daily supplementation of either 3 or 6 grams of D-aspartic acid decreased total and free testosterone in resistance-trained men and had no effect on related hormones such as estrogen or sex-hormone binding globulin (Nutrition Research, 2013 & Journal of the International Society of Sports Nutrition, 2015.)

Another example is Tribulus terrestris, often recommended for increasing testosterone. Tribulus terrestris is an herb that was first cultivated on the Steppes of Georgia (the country, not the state). East Bloc athletes used it to support testosterone production and improve performance. Russian scientists theorized that the herb acts like the pituitary hormone (LH) to stimulate testosterone release in the testes. The supplement has been extremely popular with bodybuilders and powerlifters for increasing performance and non-athletic men for improving sexual performance, even though little research supports its effectiveness. Well-controlled studies have found that tribulus has no effect on strength, body composition, or testosterone. (Journal of Human Kinetics, 2014).

According to Halis Akturk and Todd Nippoldt from the Mayo Clinic (JAMA, 2016), “The symptoms linked to low testosterone levels can often be improved through exercise, fat loss, improved diet, reduced stress and better sleep habits.”*

When it comes to diet, low-fat diets lower testosterone levels. Saturated and monounsaturated fatty acids have been shown to directly and systematically support testosterone while polyunsaturated fats, by and large, inhibit testosterone production. Arachidonic acid, an omega-6 derived polyunsaturated fatty acid, does support testosterone production, and is not recommended as a dietary supplement because it is a substrate for the inflammatory cascade and inflammation in the body. You get all the arachidonic acid you need from the diet. No need to take supplemental arachidonic acid, as it may increase inflammation and the risk of heart disease and other degenerative diseases*. The best and healthiest fats for supporting testosterone are monounsaturated fats, which are found preferably in extra-virgin olive oil, avocados and nuts. Not saturated fats, which can increase the risk of cardiovascular disease. Nuts are high in zinc and magnesium. Diets deficient in zinc can lower testosterone levels. Zinc supplements have also been shown to support testosterone in zinc-deficient adults. Also, oral zinc supplements support total and free testosterone levels in elite athletes after exhaustion exercise. (Neuro Endocrin, 2006.)*

Studies have shown that oleuropein, a polyphenol in olive oil, has aromatase-inhibiting properties, which might support testosterone levels. Also, the polyphenols found in red wine are natural aromatase inhibitors that decrease serum estrogen levels. Don’t overdo the red wine – it contains alcohol, which can lower testosterone and increase aromatase and estrogen levels! Red wine polyphenol supplements might be an alcohol-free alternative*. Alcohol can act as an aromatase stimulator and increase estrogen levels. Moderate consumption of red wine, one to two glasses per day, has a favorable effect on testosterone, unlike other alcoholic beverages, because of red wine’s polyphenol content.

The polyphenol content of red wine is one of the health benefits of the Mediterranean Diet. A breakthrough study in the American Heart Association journal Circulation conducted at Ben-Gurion University of the Negev and Harvard University, compared body fat. Researchers compared a low-fat diet to a low-carb Mediterranean Diet. The low-carb Mediterranean Diet is more effective for reducing body fat, particularly visceral (abdominal) body fat. The diet study used magnetic resonance imaging (MRI) technology for the first time, measuring changes in body fat and organ fat during 18 months on a Mediterranean low-carb diet with moderate physical exercise. This is the best approach to date for measuring body fat compared to weighing people, as opposed to diet and exercise.

The scale, skinfold calipers and underwater weighing aren’t giving you the whole picture. The Mediterranean Diet is significantly superior to a low-fat diet in decreasing fat storage including visceral (deep abdominal) liver and heart fat. High visceral fat has been shown to increase metabolic syndrome, inflammation, cardiovascular disease and diabetes. Losing deep subcutaneous visceral fat as well as hepatic (liver) fat was shown to improve lipid sensitivity and lipid profiles.

The low-carb Mediterranean diet is higher in monounsaturated fats from olive oil that can raise testosterone, while low-fat diets lower testosterone production. So not only is the low-carb Mediterranean Diet ideal for weight loss, but you get healthier fats from monounsaturated fats such as olive oil and nuts, which can support testosterone. According to a most recent study in the prestigious NEJM, (New England Journal of Medicine, June 13, 2018) persons at high cardiovascular risk, the incidents of major cardiovascular events was lower among those on a Mediterranean Diet supplemented with extra-virgin-olive-oil or nuts compared to a reduced fat diet.*

So, if you want to support testosterone and enhance fat loss, follow the low-carb Mediterranean Diet. * Recently, a study published in JAMA on April 25, 2018 found that the Mediterranean diet fights against frailty. It’s just another study that supports the Mediterranean diet to preserve lean body mass and health during aging. It’s also especially important to follow a high-intensity resistance training program for supporting testosterone and enhancing lean body mass. Don’t overdo long periods of cardiovascular, aerobic exercise as it can lower testosterone and encourage overtraining. Overtraining can lower testosterone and raise cortisol. Rest and recovery are important in supporting normal, healthy testosterone levels.*

Coffee is also good for supporting testosterone. A Harvard University study led by Nichole Wedick showed that men who drink caffeinated coffee show increases in total testosterone and decreases in free-estradiol (estrogen). Coffee is loaded with phenolic antioxidants that act as natural aromatase inhibitors, which prevent the conversion of testosterone to estrogen (Nutrition Journal, 2012). Among men, consumption of caffeinated coffee has been shown to raise testosterone levels and decrease total estrogen and estradiol levels.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

References:

Liu, TC., Lin, CH., Huang, CY. et al. Effect of acute DHEA administration on free testosterone in middle-aged and young men following high-intensity interval training. Eur J Appl Physiol (2013) 113(7): 1783-92. https://doi.org/10.1007/s00421-013-2607-x

Villareal DT, Holloszy JO. Effect of DHEA on Abdominal Fat and Insulin Action in Elderly Women and Men A Randomized Controlled Trial. JAMA. 2004;292(18):2243–2248. doi:10.1001/jama.292.18.2243

Tarig Elraiyah, Mohamad Bassam Sonbol, Zhen Wang, Tagwa Khairalseed, Noor Asi, Chaitanya Undavalli, Mohammad Nabhan, Osama Altayar, Larry Prokop, Victor M. Montori, Mohammad Hassan Murad; The Benefits and Harms of Systemic Dehydroepiandrosterone (DHEA) in Postmenopausal Women With Normal Adrenal Function: A Systematic Review and Meta-analysis, The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 10, 1 October 2014, Pages 3536–3542, https://doi.org/10.1210/jc.2014-2261

Collomp, C. Buisson, F. Lasne, R. Collomp, DHEA, physical exercise and doping, The Journal of Steroid Biochemistry and Molecular Biology, Volume 145, 2015, Pages 206-212,

Luboslav Stárka, Michaela Dušková, Martin Hill, Dehydroepiandrosterone: A neuroactive steroid, The Journal of Steroid Biochemistry and Molecular Biology, Volume 145, 2015, Pages 254-260, ISSN 0960-0760, https://doi.org/10.1016/j.jsbmb.2014.03.008.

Claes Ohlsson, Liesbeth Vandenput, Åsa Tivesten, DHEA and mortality: What is the nature of the association? The Journal of Steroid Biochemistry and Molecular Biology,Volume 145, 2015, Pages 248-253, ISSN 0960-0760, https://doi.org/10.1016/j.jsbmb.2014.03.006.

Giovanni Corona, Giulia Rastrelli, Vito A. Giagulli, Annamaria Sila, Alessandra Sforza, Gianni Forti, Edoardo Mannucci, Mario Maggi; Dehydroepiandrosterone Supplementation in Elderly Men: A Meta-Analysis Study of Placebo-Controlled Trials, The Journal of Clinical Endocrinology & Metabolism, Volume 98, Issue 9, 1 September 2013, Pages 3615-3626, https://doi.org/10.1210/jc.2013-1358

Jankowski, C.M., Gozansky, W.S., Van Pelt, R.E., Wolfe, P., Schwartz, R.S. and Kohrt, W.M. (2011), Oral dehydroepiandrosterone replacement in older adults: effects on central adiposity, glucose metabolism and blood lipids. Clinical Endocrinology, 75: 456-463. doi:10.1111/j.1365-2265.2011.04073.x

Joanna Karbowska, Zdzislaw Kochan. Fat-reducing effects of dehydroepiandrosterone involve upregulation of ATGL and HSL expression, and stimulation of lipolysis in adipose tissue, Steroids, Volume 77, Issue 13, 2012, Pages 1359-1365, ISSN 0039-128X, https://doi.org/10.1016/j.steroids.2012.08.002.

A J Morales, J J Nolan, J C Nelson, S S Yen. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age, The Journal of Clinical Endocrinology & Metabolism, Volume 78, Issue 6, 1 June 1994, Pages 1360–1367,

Yokokawa T, Sato K, Iwanaka N, Honda H, Higashida K, Iemitsu M, Hayashi T, Hashimoto T. Dehydroepiandrosterone activates AMP kinase and regulates GLUT4 and PGC-1α expression in C2C12 myotubes. Biochem Biophys Res Commun. 2015 Jul 17-24;463(1-2) 42-47. doi:10.1016/j.bbrc.2015.05.013. PMID: 25983323.

Rutkowski, K., Sowa, P., Rutkowska-Talipska, Dehydroepiandrosterone (DHEA): Hypes and Hopes J. et al. Drugs (2014) 74: 1195. https://doi.org/10.1007/s40265-014-0259-8

Luboslav Stárka, Michaela Dušková, Martin Hill, Dehydroepiandrosterone: A neuroactive steroid, The Journal of Steroid Biochemistry and Molecular Biology, Volume 145, 2015, Pages 254-260, https://doi.org/10.1016/j.jsbmb.2014.03.008.

Alhaj, H.A., Massey, A.E. & McAllister-Williams, R.H. Effects of DHEA administration on episodic memory, cortisol and mood in healthy young men: a double-blind, placebo-controlled study. Psychopharmacology (2006) 188: 541. https://doi.org/10.1007/s00213-005-0136-y

Thuzar M, Law WP, Ratnasingam J, Jang C, Dimeski G, Ho KKY. Glucocorticoids suppress brown adipose tissue function in humans: A double‐blind placebo‐controlled study. Diabetes Obes Metab. 2018;20:840–848. https://doi.org/10.1111/dom.13157

Hough CM, Lindqvist D, Epel ES, et al. Higher serum DHEA concentrations before and after SSRI treatment are associated with remission of major depression. Psychoneuroendocrinology. 2017;77:122-130. doi:10.1016/j.psyneuen.2016.11.035.

Sex hormones and sarcopenia in older persons. Maggio, Marcelloa, B; Lauretani, Fulviob; Ceda, Gian Paolo, Current Opinion in Clinical Nutrition & Metabolic Care: January 2013 - Volume 16 - Issue 1 - p 3-13 doi: 10.1097/MCO.0b013e32835b6044

Baker, W.L., Karan, S. and Kenny, A.M. (2011), Effect of Dehydroepiandrosterone on Muscle Strength and Physical Function in Older Adults: A Systematic Review. Journal of the American Geriatrics Society, 59: 997-1002. doi:10.1111/j.1532-5415.2011.03410.x

DHEA enhances effects of weight training on muscle mass and strength in elderly women and men Dennis T. Villareal and John O. Holloszy, American Journal of Physiology-Endocrinology and Metabolism 2006 291:5, E1003-E1008

Naghii M R, Mofid M, Asgari A R, Hedayati M, Daneshpour M S. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines. Physiol Pharmacol. 2011; 15 (3) :403-414

Nielsen FH, Hunt CD, Mullen LM, Hunt JR. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women. FASEB J 1987; 1:394-7

Naghii MR, Samman S. The effect of boron supplementation on the distribution of boron in selected tissues and on testosterone synthesis in rats. J Nutr Biochem 1996;7:507–12

Nielsen FH. The emergence of boron as nutritionally important throughout the life cycle. Nutrition 2000;16:512–4.

Wilborn C, Taylor L, Poole C, Foster C, Willoughby D, Kreider R. Effects of a purported aromatase and 5α-reductase inhibitor on hormone profiles in college-age men. Int J Sport Nutr Exerc Metab. 2010 Dec;20(6):457-65.

Sachin Wankhede, Vishwaraman Mohan, Prasad Thakurdesai, Beneficial effects of fenugreek glycoside supplementation in male subjects during resistance training: A randomized controlled pilot study, Journal of Sport and Health Science, Volume 5, Issue 2, 2016, Pages 176-182.

Mohammed R. Haeri, Hamidreza Khalatbari Limaki, Christopher J. Branford White, Kenneth N. White, Non-insulin dependent anti-diabetic activity of (2S, 3R, 4S) 4-hydroxyisoleucine of fenugreek (Trigonella foenum graecum) in streptozotocin-induced type I diabetic rats, Phytomedicine, Volume 19, Issue 7, 2012, Pages 571-574.

Tambi, M.I., Imran, M.K. and Henkel, R.R. (2012), Standardized water‐soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late‐onset hypogonadism? Andrologia, 44: 226-230. doi:10.1111/j.1439-0272.2011.01168.x

Henkel, R.R., Wang, R., Bassett, S.H., Chen, T., Liu, N., Zhu, Y. and Tambi, M.I. (2014), Tongkat Ali as a Potential Herbal Supplement for Physically Active Male and Female Seniors – A Pilot Study. Phytother. Res., 28: 544-550. doi:10.1002/ptr.5017

George A, Henkel R. Phytoandrogenic properties of Eurycoma Longifolia as natural alternative to testosterone replacement therapy. Andrologia. 2014 Sep; 46(7):708-21.

Talbott SM, Talbott JA, George A, Pugh M. Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects. Journal of the International Society of Sports Nutrition. 2013;10:28. doi:10.1186/1550-2783-10-28.

Tambi MI. Eurycoma Longifolia jack: a potent adaptogen in the form of water-soluble extract with the effect of maintaining men’s health. Asian J Androl 2006; 8 (Suppl 1):49-50.

World Health Organization (WHO) Laboratory Manual for the Examination of Human Semen and Sperm - Cervical Mucus Interaction. New York: Cambridge University Press; 1999

Bin-Seng Low, Sy-Bing Choi, Habibah Abdul Wahab, Prashanta Kumar Das, Kit-Lam Chan, Eurycomanone, the major quassinoid in Eurycoma longifolia root extract increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis, Journal of Ethnopharmacology, Volume 149, Issue 1, 2013, Pages 201-207, https://doi.org/10.1016/j.jep.2013.06.023.

Zanoli P, Zavatti M, Montanari C, Baraldi M: Influence of Eurycoma longifolia on the copulatory activity of sexually sluggish and impotent male rats. J Ethnopharmacol 2009, 126:308–313.

Chaing HS, Merino-Chavez G, Yang LL, Wang FN, Hafez ES: Medicinal plants: conception/contraception. Adv Contracept Deliv Syst 1994, 10(3-4):355-63.

Tambi MI: Water soluble extract of Eurycoma longifolia in enhancing testosterone in males. In Proceedings of the SupplySide West International Trade Show and Conference. Virgo Publishing; 2003. Oct 1-3.

Hamzah S, Yusof A: The ergogenic effects of Tongkat ali (Eurycoma longifolia): A pilot study. British J Sports Med 2003, 37:464-470.

Sarina MY, Zaiton Z, Aminudin AHK, Nor AK, Azizol AK: Effects of resistance training and Eurycoma longifolia on muscle strength, lipid profile, blood glucose, and hormone level in middle-aged women. In 4th Asia-Pacific Conference on Exercise and Sport Science & 8th International Sports Science Conference. Academy of Medicine of Malaysia; 2009

Ismail SB, Wan Mohammad WM, George A, Nik Hussain NH, Musthapa Kamal ZM, Liske ZM: Randomized clinical trial on the Use of PHYSTA freeze-dried water extract of eurycoma longifolia for the improvement of quality of life and sexual well-being in Men. Evid Based Complement Alternat Med; 2012. doi:10.1155/2012/429268.

Talbott S, Talbott J, Negrete J, Jones M, Nichols M, Roza J: Effect of eurycoma longifolia extract on anabolic balance during endurance exercise [abstract]. J Int Soc Sports Nutr 2006, 3(1):S32.

Tambi MI: Glycoprotein water-soluble extract of Eurycoma longifolia Jack as a health supplement in management of healthy aging in aged men. The Aging Male 2003, 6(1):41-70

Tambi MI: Standardized water-soluble extract of Eurycoma longifolia maintains healthy aging in man. The Aging Male 2007, 10(2):77-87.

Shufelt C, Merz CNB, Yang Y, et al. Red Versus White Wine as a Nutritional Aromatase Inhibitor in Premenopausal Women: A Pilot Study. Journal of Women’s Health. 2012;21(3):281-284. doi:10.1089/jwh.2011.3001.

Carl Jenkinson, Andrea Petroczi, Declan P Naughton. Red wine and component flavonoids inhibit UGT2B17 in vitro. Nutrition Journal, 2012; 11 (1): 67 DOI: 10.1186/1475-2891-11-67.

Jenkinson C, Petroczi A, Naughton DP. Effects of Dietary Components on Testosterone Metabolism via UDP-Glucuronosyltransferase. Frontiers in Endocrinology. 2013;4:80. doi:10.3389/fendo.2013.00080.

Wang Y, Lee K, et al. The red wine polyphenol resveratrol displays bilevel inhibition on aromatase in breast cancer cels. Toxicol Sci 2006;92: 71-7

Balunas MJ, Su B, Brueggemeier RW, Kinghorn AD. Natural Products as Aromatase Inhibitors. Anti-cancer agents in medicinal chemistry. 2008;8(6):646-682. Suppression of aromatase (estrogen synthetase) by red wine phytochemicals. Eng, Elizabeth T. 1; Williams, Dudley 1; Mandava, Usha 2; Kirma, Nimeer 2; Tekmal, Rajeshwar Rao 2; Chen, Shiuan 1 Breast Cancer Research & Treatment. 67(2):133-146, May 2001.

ENG, E.T., WILLIAMS, D., MANDAVA, U., KIRMA, N., TEKMAL, R.R. and CHEN, S. (2002), Anti‐Aromatase Chemicals in Red Wine. Annals of the New York Academy of Sciences, 963: 239-246. doi:10.1111/j.1749-6632.2002.tb04116.x

In Vitro Inhibition of Human cGMP-Specific Phosphodiesterase-5 by Polyphenols from Red Grapes Mario Dell'Agli,*,†, Germana V. Galli,†, Urska Vrhovsek,§, Fulvio Mattivi,§ and, and Enrica Bosisio† Journal of Agricultural and Food Chemistry 2005 53 (6), 1960-1965 DOI: 10.1021/jf048497+

Yun Wang, Kai Woo Lee, Franky L. Chan, Shiuan Chen, Lai K. Leung; The Red Wine Polyphenol Resveratrol Displays Bilevel Inhibition on Aromatase in Breast Cancer Cells, Toxicological Sciences, Volume 92, Issue 1, 1 July 2006, Pages 71-77, https://doi.org/10.1093/toxsci/kfj190

Suppression of Estrogen Biosynthesis by Procyanidin Dimers in Red Wine and Grape Seeds Elizabeth T. Eng, JingJing Ye, Dudley Williams, Sheryl Phung, Roger E. Moore, Mary K. Young, Ugis Gruntmanis, Glenn Braunstein and Shiuan Chen Cancer Res December 1 2003 (63) (23) 8516-8522.

Modulation of aromatase activity by diet polyphenolic compounds. Rosário Monteiro, Isabel Azevedo, Conceição Calhau. J Agric Food Chem. 2006 May 17; 54(10): 3535-3540.

Grape Seed Extract Is an Aromatase Inhibitor and a Suppressor of Aromatase Expression. Ikuko Kijima, Sheryl Phung, Gene Hur, Sum-Ling Kwok and Shiuan Chen. Cancer Res June 1 2006 (66) (11) 5960-5967; DOI: 10.1158/0008-5472.CAN-06-0053.

Kao YC, Zhou C, Sherman M, Laughton CA, Chen S. Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study. Environmental Health Perspectives. 1998;106(2):85-92.

Castillo-Pichardo L, Martínez-Montemayor MM, Martínez JE, Wall KM, Cubano LA, Dharmawardhane S. Inhibition of mammary tumor growth and metastases to bone and liver by dietary grape polyphenols. Clinical & experimental metastasis. 2009;26(6):505-516. doi:10.1007/s10585-009-9250-2.

Pilz, S.; Frisch, S.; Koertke, H.; Kuhn, J.; Dreier, J.; Obermayer-Pietsch, B.; Wehr, E.; Zittermann, A. Effect of Vitamin D Supplementation on Testosterone Levels in Men. Hormone and Metabolic Research 2011; 43(03): 223 – 225 DOI: 10.1055/s-0030-1269854

Vitamin D and Nandrolone Increase Androgen Receptors. (Paper presented at annual meeting of the Endocrine Society, June 4, 2011.)

Effects of vitamin D supplementation on upper and lower body muscle strength levels in healthy individuals. A systematic review with meta-analysis Tomlinson, Peter B. et al. Journal of Science and Medicine in Sport, Volume 18 , Issue 5 , 575-580

Chang E and Kim Y. Vitamin D decreases adipocyte lipid storage and increases NAD-SIRTI pathway in 3T3-LI adipocytes. Nutrition 2016;32, 702-708.

Carrillo AE, Flynn MG, Pinkston C, et al. Impact of vitamin D supplementation during a resistance training intervention on body composition, muscle function, and glucose tolerance in overweight and obese adults. Clinical nutrition (Edinburgh, Scotland). 2013;32(3):375-381. doi:10.1016/j.clnu.2012.08.014.

Salehpour A, Hosseinpanah F, et al. A 12-week double-blind randomized clinical trial of vitamin D3 supplementation on body fat mass in healthy overweight and obese women. Nutr. J 2014; 11, 78.

Pereira‐Santos, M., Costa, P.R., Assis, A.M., Santos, C.A. and Santos, D.B. (2015), Obesity and vitamin D. Obes Rev, 16: 341-349. doi:10.1111/obr.12239

Three and six grams supplementation of d-aspartic acid in resistance trained men. Geoffrey W Melville, Jason C Siegler and Paul WM Marshall Journal of the International Society of Sports Nutrition 2015,12:15 https://doi.org/10.1186/s12970-015-0078-7

Darryn S. Willoughby, Brian Leutholtz, d-Aspartic acid supplementation combined with 28 days of heavy resistance training has no effect on body composition, muscle strength, and serum hormones associated with the hypothalamo-pituitary-gonadal axis in resistance-trained men, Nutrition Research, Volume 33, Issue 10, 2013, Pages 803-810, https://doi.org/10.1016/j.nutres.2013.07.010

Insights into Supplements with Tribulus Terrestris used by Athletes. Andrzej Pokrywka1, Zbigniew Obmiński2, Jadwiga Malczewska-Lenczowska3, Zbigniew Fijałek4, Ewa Turek-Lepa1, Ryszard Grucza5 Journal of Human Kinetics volume 41/2014, 99-105 DOI: 10.2478/hukin-2014-0037 9

Akturk HK, Nippoldt TB. Low Testosterone in Men Should Be a Sign Rather Than a Number to IncreaseA Teachable Moment. JAMA Intern Med. 2016;176(12):1743-1744. doi:10.1001/jamainternmed.2016.5761.

Abudayyak, A.T. Jannuzzi, G. Özhan & B. Alpertunga (2014). Investigation on the toxic potential of Tribulus terrestris in vitro, Pharmaceutical Biology, 53:4, 469-476, DOI: 10.3109/13880209.2014.924019

Aksu, E.H., Akman, O., Ömür, A.D., Karakuş, E., Can, İ., Kandemir, F.M., Dorman, E. and Uçar, Ö. (2016), 3,3 diindolylmethane leads to apoptosis, decreases sperm quality, affects blood estradiol 17 β and testosterone, oestrogen (α and β) and androgen receptor levels in the reproductive system in male rats. Andrologia, 48: 1155-1165. doi:10.1111/and.12554

Plant-derived 3,3′-Diindolylmethane Is a Strong Androgen Antagonist in Human Prostate Cancer Cells J. Biol. Chem. 2003 278: 21136-. doi:10.1074/jbc.M300588200

Endocrine Disruption throughout the Hypothalamus-Pituitary-Gonadal-Liver (HPGL) Axis in Marine Medaka (Oryzias melastigma) Chronically Exposed to the Antifouling and Chemopreventive Agent, 3,3′-Diindolylmethane (DIM.) Lianguo Chen, Rui Ye, Weipeng Zhang, Chenyan Hu, Bingsheng Zhou, Drew R. Peterson, Doris W. T. Au, Paul K. S. Lam, and Pei-Yuan Qian. Chemical Research in Toxicology 2016 29 (6), 1020-1028 DOI: 10.1021/acs.chemrestox.6b00074

Yftach Gepner, Ilan Shelef, Dan Schwarzfuchs, Hila Zelicha, Lilac Tene, Anat Yaskolka Meir, Gal Tsaban, Noa Cohen, Nitzan Bril, Michal Rein, Dana Serfaty, Shira Kenigsbuch, Oded Komy, Arik Wolak, Yoash Chassidim, Rachel Golan, Hilla Avni-Hassid, Avital Bilitzky, Benjamin Sarusi, Eyal Goshen, Elad Shemesh, Yaakov Henkin, Michael Stumvoll, Matthias Blüher, Joachim Thiery, Uta Ceglarek, Assaf Rudich, Meir J. Stampfer, Iris Shai. Effect of Distinct Lifestyle Interventions on Mobilization of Fat Storage Pools: The CENTRAL MRI Randomized Controlled Trial. Circulation, 2017; CIRCULATIONAHA.117.030501 DOI: 10.1161/CIRCULATIONAHA.117.030501

Voelker R. The Mediterranean Diet’s Fight Against Frailty. JAMA. 2018;319(19):1971–1972. doi:10.1001/jama.2018.3653

Weight Loss with a Low-Carbohydrate, Mediterranean, or Low-Fat Diet. Iris Shai, R.D., Ph.D., Dan Schwarzfuchs, M.D., Yaakov Henkin, M.D., Danit R. Shahar, R.D., Ph.D., Shula Witkow, R.D., M.P.H., Ilana Greenberg, R.D., M.P.H., Rachel Golan, R.D., M.P.H., Drora Fraser, Ph.D., Arkady Bolotin, Ph.D., Hilel Vardi, M.Sc., Osnat Tangi-Rozental, B.A., Rachel Zuk-Ramot, R.N., Benjamin Sarusi, M.Sc., Dov Brickner, M.D., Ziva Schwartz, M.D., Einat Sheiner, M.D., Rachel Marko, M.Sc., Esther Katorza, M.Sc., Joachim Thiery, M.D., Georg Martin Fiedler, M.D., Matthias Blüher, M.D., Michael Stumvoll, M.D., and Meir J. Stampfer, M.D., Dr.P.H., for the Dietary Intervention Randomized Controlled Trial (DIRECT) Group N Engl J Med 2008; 359:229-241July 17, 2008DOI: 10.1056/NEJMoa0708681

The effect of dietary oleic, linoleic, and linolenic acids on fat oxidation and energy expenditure in healthy men. Jones, Peter J.H. et al. Metabolism - Clinical and Experimental, Volume 57, Issue 9, 1198-1203

Nut intake and 5-year changes in body weight and obesity risk in adults: results from the EPIC-PANACEA study. European Journal of Nutrition, 2017, Page 1 Heinz Freisling, Hwayoung Noh, Nadia Slimani,

Oleuropein, a Phenolic Compound in Extra Virgin Olive Oil, Increases Uncoupling Protein 1 Content in Brown Adipose Tissue and Enhances Noradrenaline and Adrenaline Secretions in Rats, Journal of Nutritional Science and Vitaminology, Released November 11, 2008 Yuriko Oi-Kano, Teruo Kawada, Tatsuo Watanabe, Fumihiro Koyama, Kenichi Watanabe, Reijirou Senbongi, Kazuo Iwai

Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts. Ramón Estruch, M.D., Ph.D., Emilio Ros, M.D., Ph.D., Jordi Salas-Salvadó, M.D., Ph.D., Maria-Isabel Covas, D.Pharm., Ph.D., Dolores Corella, D.Pharm., Ph.D., Fernando Arós, M.D., Ph.D., Enrique Gómez-Gracia, M.D., Ph.D., Valentina Ruiz-Gutiérrez, Ph.D., Miquel Fiol, M.D., Ph.D., José Lapetra, M.D., Ph.D., Rosa M. Lamuela-Raventos, D.Pharm., Ph.D., Lluís Serra-Majem, M.D., Ph.D., et al., for the PREDIMED Study Investigators. New England Journal of Medicine (NEJM) June 13, 2018 https://www.nejm.org/doi/full/10.1056/NEJMoa1800389

Fungwe TV, et al. Stimulation of fatty acid biosynthesis by dietary cholesterol and of cholesterol synthesis by dietary fatty acid. J Lipid Res 1994; 35(2): 311-8

Hrtado de Catalfo GE, de Alaniz MJ, et al. Influence of commercial dietary oils on lipid composition and testoerone production in interstitial cells isolated from rat testis. Lipids 2009; 44(4): 345-57.

The effect of exhaustion exercise on thyroid hormones and testosterone levels of elite athletes receiving oral zinc. Kilic M1, Baltaci AK, Gunay M, Gökbel H, Okudan N, Cicioglu, Neuro Endocrinol Lett. 2006 Feb-Apr;27(1-2):247-52.

Zinc status and serum testosterone levels of healthy adults. A. S. Prasad, C. S. Mantzoros, F. W. Beck, J. W. Hess, G. J. Brewer, Nutrition. 1996 May; 12(5): 344-348.

The effects of caffeinated and decaffeinated coffee on sex hormone-binding globulin and endogenous sex hormone levels: a randomized controlled trial. Nicole M WedickEmail author, Christos S Mantzoros, Eric L Ding, Aoife M Brennan, Bernard Rosner, Eric B Rimm, Frank B Hu and Rob M van Dam, Nutrition Journal201211:86 https://doi.org/10.1186/1475-2891-11-86

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