Please ensure Javascript is enabled for purposes of website accessibility Citrulline and Exercise Increase Performance

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Exercise and the amino acid citrulline are important regulators of muscle protein synthesis. Citrulline is a popular component in athletic food supplements because it participates in key amino acid reactions and influences blood flow by increasing nitric oxide levels. Nitric oxide is an important chemical secreted by the endothelium— the inner lining of the blood vessels. Arthur Goron from the University of Grenoble in France, and colleagues, found that endurance exercise and citrulline by themselves increased performance, but the combination of the supplement and training increased performance even more. (Clinical Science, published online March 1, 2017)