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science nutrition blog

science nutrition <strong>blog</strong>

Conjugated linoleic acid (CLA) is a controversial weight-loss supplement. Early rat studies showed measurable and rapid changes in body composition. However, human trials are less convincing. A recent review entitled “Effects of conjugated linoleic acid supplementation on serum C-reactive protein: A Systematic Review and meta-analysis of Randomized Controlled Trials” stated: “This meta-analysis suggests that CLA supplementation is associated with an increase in plasma CRP concentrations and a reduction in serum adiponectin concentrations, which indicates that CLA supplements have a pro-inflammatory effect.” C-reactive protein (CRP) is a measure of inflammation in the body. High CRP is associated with a higher risk for cardiovascular disease. (Cardiovascular Therapeutics, May 29, 2017)