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Conjugated linoleic acid (CLA) is a controversial weight-loss supplement. Early rat studies showed measurable and rapid changes in body composition. However, human trials are less convincing. A recent review entitled "Effects of conjugated linoleic acid supplementation on serum C-reactive protein: A Systematic Review and meta-analysis of Randomized Controlled Trials" stated: "This meta-analysis suggests that CLA supplementation is associated with an increase in plasma CRP concentrations and a reduction in serum adiponectin concentrations, which indicates that CLA supplements have a pro-inflammatory effect." C-reactive protein (CRP) is a measure of inflammation in the body. High CRP is associated with a higher risk for cardiovascular disease. (Cardiovascular Therapeutics, May 29, 2017)

CLA Supplements and Their Impact on Inflammatory Response

June 05, 2017

Recent scientific research has explored the potential effects of CLA supplements, particularly focusing on conjugated linoleic acid and its role in the body's inflammatory response. While these supplements are popular for their purported health benefits, it's essential to consider the possible CLA side effects, including those related to inflammation. A systematic review of existing studies may provide further insights into conjugated linoleic acid side effects and its relationship with inflammation.