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science nutrition <strong>blog</strong>

Glucosamine and chondroitin sulphate supplements reduced knee cartilage loss in some patients— according to a study by Canadian researchers. Cartilage loss is linked to knee arthritis and eventual joint replacement. This study is at odds with a study led by Kent Kwoh from the University of Pittsburgh, which found that people with mild to moderate knee pain did not benefit from taking glucosamine (1,500 milligrams per day) for six months. Several research studies found that glucosamine and chondroitin supplements promote the growth of cartilage cells. Cartilage is vital for functional, pain-free joints. Worldwide, people spent nearly $2 billion per year on glucosamine-chondroitin supplements. They have a strong placebo effect— people want them to work, so they do. The best way to reduce arthritis pain is to exercise sensibly and maintain an ideal weight. We need more information before we can recommend these supplements. (Annals of the Rheumatic Diseases, 74: 547, 2015)