Glucosamine Promotes Joint Health in People With Arthritis
Arthritis is a crippling disorder of the joints that affects cartilage, underlying bone, joint lubrication, and surrounding muscles. Many people take glucosamine to promote cartilage health and reduce arthritis pain, but studies have not shown a consistently beneficial effect. A Danish study showed that glucosamine (500 mg three times per day for 12 weeks) decreased levels of cartilage oligomeric matrix protein, which is linked to cartilage and joint deterioration and arthritis. Subjects were involved in a 12-week strength-training program and were given glucosamine, Ibuprofen (e.g., Advil) or placebo (fake supplements). Glucosamine improves cartilage health in the knee joint when combined with a weight-training program. (Osteoarthritis and Cartilage, 18: 34e40, 2010)