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science nutrition blog

science nutrition <strong>blog</strong>

 By Steve Blechman


What is NO3? Nitric oxide (NO) is the gaseous molecule that is produced naturally in the body. It plays an important role in human health. NO is involved in many important signaling and regulatory processes controlling numerous vascular and cellular functions in the human body. One important function is vasodilation caused by relaxing and widening of blood vessels, enhancing blood flow, circulation and delivery of nutrients and oxygen to muscles and the entire body. NO plays an important role in cardiovascular health, erectile function, and exercise performance.

NO-enhanced increase in blood flow may enhance skeletal muscle performance, muscle hypertrophy, and strength adaptations. It may also delay fatigue and provide greater training volume and anabolic signaling and stimulus of muscle protein synthesis.

“Nitric oxide stimulating dietary supplements are widely available and marketed to strength athletes and weightlifters seeking to increase muscle performance and augment training adaptations. These supplements contain ingredients classified as nitric oxide (NO) precursor (i.e., “NO boosters”).” (Nutrients, January 28, 2023)

The most popular NO precursors include the amino acid L-citrulline or citrulline malate, which provides one of the body’s two nitric oxide pathways (citrulline arginine pathway). The other pathway is the nitrate-nitrite pathway. Both pathways boost nitric oxide, which may enhance exercise performance.

Nitrates (NO3) have become increasingly popular for their potential role as an ergogenic aid” and improving human performance.

A review of the scientific literature has shown that nitrate taken acutely or chronically in the range up 300 to 1,041 milligrams two to three hours before exercise is an effective ergogenic aid. (Nutrients, September 13, 2021)

Research has shown that for muscle strength gains a minimum acute dose of 400 milligrams of nitrate (NO3) provides the best results. (Journal of Strength and Conditioning Research, December 1, 2022)


Introducing Advanced Molecular Labs (AML) NITRATE NO3 BOOSTER, a high-performance, scientifically advanced, super nitrate (NO3) formula. It contains patented citrulline nitrate (NO3T®), a patented nitric oxide (NO) booster that promotes nitric oxide by two pathways (L-citrulline and nitrate) in a single ingredient.†

Citrulline nitrate is a unique nitric oxide-boosting compound containing the amino acid L-citrulline, specifically bonded to nitrate. Nitrate is naturally found in red beets, spinach, kale, and arugula and is converted to nitric oxide in the body. Citrulline is found in a number of foods such as watermelon and as a dietary supplement is superior to L-arginine for increasing blood levels of arginine. Therefore, L-citrulline is more effective than L-arginine for boosting nitric oxide production.†

Arginine is a precursor, which the body uses to generate nitric oxide – an important signaling molecule that may improve muscular function and exercise performance. Nitric oxide (NO) enhances vasodilation (widening of blood vessels), which may favorably impact greater blood flow, oxygen and nutrient delivery to working muscles.†

Greater nitric oxide (NO) production supports better muscle pumps! Nitric oxide (NO) may also enhance energy production, work capacity, time to exhaustion and increasing the number of repetitions performed in the gym during training.†

AML NITRATE (NO3) BOOSTER capsules contain 2000mg of citrulline nitrate per dose (standardized for 27% nitrate providing 540mg nitrate).

AML NITRATE (NO3) BOOSTER also contains a science-based, synergistic blend of nitric oxide-boosting vitamins, antioxidants and polyphenols: Folic Acid, Vitamin B-12, Vitamin C, Pine Bark Extract (standardized for 95% Proanthocyanidins), and Grape Skin Extract (standardized for 30% polyphenols), to help maximize and support nitric oxide (NO) production and bioavailability.†

For Best results, AML NITRATE (NO3) BOOSTER capsules can be taken 1-1½ hours before exercise with AML PREWORKOUT or AML PREWORKOUT X-TREME.

AML NITRATE (NO3) BOOSTER capsules can also be taken 1-1½ hours before bedtime with AML SEX COCKTAIL for better sexual performance in the bedroom.

If preferred, capsules can be opened and added to AML Preworkout or AML Sex Cocktail.

© Published by Advanced Research Media, Inc. 2023

© Reprinted with permission from Advanced Research Media, Inc.


† These statements have not been evaluated by the Food and Drug administration. This product is not intended to diagnose, treat, cure or prevent any disease.



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