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‘THE GAME CHANGERS’ A MISLEADING DOCUMENTARY: GOOD FOR VEGANISM, BAD FOR BUILDING MUSCLE

Brian Turner

Posted on February 29 2020

By Steve Blechman

 

            I have been an advocate of the Mediterranean diet (fish, extra virgin olive oil, fruits, vegetables, nuts, beans, and lentils) for over 20 years for achieving optimal health, weight loss and prevention of degenerative diseases including heart disease and cancer.  A documentary called “The Game Changers” is a movie about the benefits of a vegan, vegetarian/plant-based diet for athletes. The film was produced by the highly acclaimed Academy Award-winner James Cameron. “The Game Changers” has had a big impact, reaching millions of viewers and created a lot of awareness, and falsely argues that an animal diet including meat, dairy (which includes whey protein), eggs and fish has a negative effect on athletic performance— and that you don’t need animal protein for optimal muscular development or growth. Nothing could be further from the truth, based on the latest scientific research. “The Game Changers” makes statements that are extremely misleading, citing small poorly designed studies and presenting only one side of the facts and scientific literature. Also, very controversial sources were interviewed, and the movie is more like a marketing ploy to promote the Green New Deal, and the vegan/vegetarian movement. The film interviewed several medical doctors and vegetarian athletes, providing a distorted view of the truth!

            An article published in Men’s Health on September 16th 2019 was entitled, “This New Documentary Says Meat Will Kill You. Here’s Why It’s Wrong.” The article noted, for example, “Its entire concept [was built] around, a study he came across that reported Roman gladiators didn’t eat meat.” Also, the study that movie cited wasn’t “actually a study.” The report said, “It’s a short narrative by Andrew Curry, a contributing writer to Archaeology, a publication of the Archaeological Institute of America.”

            James Wilds, a former MMA fighter, states in the movie, “And when it comes to gaining strength and muscle mass, research comparing plant and animal protein has shown that as long as the proper amount of amino acids are consumed the source is irrelevant.”

            This statement is untrue when it comes to bodybuilding and building muscle you need to consume a sufficient amount of protein to enhance muscle growth. Bodybuilders need to consume a sufficient amount of protein daily to enhance muscle growth. Optimum muscle building nutrition promotes muscle growth and a response to intense strength training by increasing and activating the mTOR (mammalian target of rapamycin) pathway; mTOR increases muscle protein synthesis while reducing protein breakdown. The branched-chain amino acid leucine is most abundant in animal proteins (whey protein is the richest food source of leucine) and lacking in vegetable proteins. The muscle-building benefits of leucine also increases mTOR.                      

Below are the muscle-building benefits of leucine:

- Leucine is the key anabolic trigger to protein synthesis.

 - Increases in muscle protein synthesis are dependent on leucine concentration.

 - 5 grams of leucine can increase the anabolic effects of protein synthesis when eating less protein, which is ideal on a ketogenic diet.

 - Research has shown 6.25 grams of whey protein with 5 grams of leucine is equivalent to at least 25 grams of whey protein, as found in AML™ THERMO HEAT® FAT BURNING PROTEIN.

 - Anabolic resistance in people over 40 can be overcome by consuming greater quantities of leucine.

 - Leucine and not total protein content of a supplement is the primary determinant of muscle protein anabolic responses in healthy older people.

 Research has shown that pure leucine is more anabolic than protein in food!

 - Leucine is the key amino acid for enhancing the mTOR pathway that regulates cell growth and protein synthesis.

 - Leucine has many benefits: powering muscle growth, preventing muscle loss and enhancing recovery.

           Research has clearly shown that vegetarian diets are less anabolic than animal proteins and lower mTOR! Vegetarian diets also lower insulin-like growth factor 1 (IGF-1), an anabolic hormone that also activates growth hormone (GH) action.          

           Vegetarian diets also can lower testosterone (especially when combined with high-intensity long duration aerobic exercise) and increase estrogen levels. The journal Endocrine Practice reported in May 2008 about a case of gynecomastia related to the ingestion of soy products. Also reported was erectile dysfunction and decreased libido. Lab tests showed a 4-fold increase in the estrogen hormones estrone and estradiol levels. Many plants including soy provide phytoestrogens and potential endocrine disruptors and functions similar to estrogen.

            Meat is also the richest natural source of creatine, an inhibitor of myostatin that can promote muscle growth and enhance exercise performance. Plants do not contain creatine. Plus, meat is the richest source of the amino acid tripeptide carnosine. Carnosine is the most important lactic acid buffer in muscle. Carnosine is also not present in plants; only in animal products.

            It was recently reported in the journal Nutrients on August 7, 2019 that plant protein has less of muscle building and anabolic effect due to lower digestibility and essential amino acids, including the branched-chain amino acids, especially leucine.

            The standard for measuring protein quality is called the digestible indispensable amino acid score (DIAAS). Animal proteins such as meat, milk (including whey protein) and eggs have higher DIAAS values than plant proteins (British Journal of Nutrition, February 24, 2020).

            Another beef I have with “The Game Changers” is how it covered several athletes, powerlifters and strength athletes that converted to vegetarianism. Were their enhanced athletic performances and feats of strength the result of their vegetarian diet, as the movie suggests? There was never any mention in the film if these athletes were drug tested for performance-enhancing drugs and anabolic steroids!

            Bottom line: my real beef with “The Game Changers” is not that they are promoting the vegetarian diet and lifestyle for better health— that’s fine. The science supports that, but “The Game Changers” only provides one side of the facts and presents a point of view that is misleading and not based on good peer-reviewed scientific research.

 

References:

  1. Paul Kita. This New Documentary Says Meat Will Kill You. Here’s Why It’s Wrong. Men’s Health, September 16, 2019.
  2. The Game Changers (2019) movie, produced by Andrew Curry and James Cameron.
  3. Berrazaga I, Micard V, Gueugneau M, Walrand S. The Role of the Anabolic Properties of Plant- versus Animal-Based Protein Sources in Supporting Muscle Mass Maintenance: A Critical Review. Nutrients 2019;11(8):1825. Published 2019 Aug 7. doi:10.3390/nu11081825
  4. Bailey HM et al. Most meat products have digestible indigestible amino acid scores that are greater than 100, but processing may increase or reduce protein quality. British Journal of Nutrition, February 24, 2020.
  5. Marinangeli C.P.F. et al. Potential impact of digestible indispensable amino acid score as a measure of protein quality on dietary regulations and health. Nutrition Reviews, 2017.
  6. Does beef protein supplementation improve body composition and exercise performance? A systematic review and meta-analysis of randomized controlled trials. Nutrients, June 25, 2019.
  7. Intake of animal protein blend plus carbohydrate improves body composition with no impact on performance in endurance athletes. Randomized controlled trial. International Journal of Sport Nutrition and Exercise Metabolism, September 1, 2019.
  8. Jorge Martinez. An unusual case of gynecomastia associated with soy product consumption. Endocrine Practice, May 2008. vol 14.
  9. Nicola Theis, Meghan A Brown, Paula Wood, Mark Waldron, Leucine Supplementation Increases Muscle Strength and Volume, Reduces Inflammation, and Affects Wellbeing in Adults and Adolescents with Cerebral Palsy, The Journal of Nutrition, nxaa006. https://doi.org/10.1093/jn/nxaa006
  10. Santos CS, Nascimento FEL. Isolated branched-chain amino acid intake and muscle protein synthesis in humans: a biochemical review. Einstein (Sao Paulo). 2019;17(3):eRB4898. Published 2019 Sep 5. doi:10.31744/einstein_journal/2019RB4898
  11. Wilkinson DJ, Hossain T, Hill DS, et al. Effects of leucine and its metabolite beta-hydroxy-beta-methylbutyrate on human skeletal muscle protein metabolism. J Physiol. June 1, 2013;591(11):2911-2923. doi:10.1113/jphysiol.2013.253203
  12. Stephen J. Crozier, Scot R. Kimball, Sans W. Emmert, Joshua C. Anthony, Leonard S. Jefferson. Oral Leucine Administration Stimulates Protein Synthesis in Rat Skeletal Muscle. The Journal of Nutrition, Volume 135, Issue 3, March 2005, Pages 376-382, https://doi.org/10.1093/jn/135.3.376
  13. Churchward-Venne TA, Burd NA, Phillips SM. Nutritional regulation of muscle protein synthesis with resistance exercise: strategies to enhance anabolism. Nutr Metab (Lond). 2012;9(1):40.
  14. Churchward-Venne TA, Burd NA, Mitchell CJ, West DW, Philp A, Marcotte GR, et al. Supplementation of a suboptimal protein dose with leucine or essential amino acids: effects on myofibrillar protein synthesis at rest and following resistance exercise in men. J Physiol. 2012;590(11):2751-65.
  15. Churchward-Venne TA, Breen L, Di Donato DM, Hector AJ, Mitchell CJ, Moore DR, et al. Leucine supplementation of a low-protein mixed macronutrient beverage enhances myofibrillar protein synthesis in young men: a double-blind, randomized trial. Am J Clin Nutr. 2014;99(2):276-86.
  16. Bukhari SS, Phillips BE, Wilkinson DJ, Limb MC, Rankin D, Mitchell WK, et al. Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women at rest and after exercise. Am J Physiol Endocrinol Metab. 2015;308(12):E1056-65.
  17. Audrey Chanet, Sjors Verlaan, Jérôme Salles, Christophe Giraudet, Véronique Patrac, Véronique Pidou, Corinne Pouyet, Nordine Hafnaoui, Adeline Blot, Noël Cano, Nicolas Farigon, Anke Bongers, Marion Jourdan, Yvette Luiking, Stéphane Walrand, Yves Boirie. Supplementing Breakfast with a Vitamin D and Leucine-Enriched Whey Protein Medical Nutrition Drink Enhances Postprandial Muscle Protein Synthesis and Muscle Mass in Healthy Older Men, The Journal of Nutrition, Volume 147, Issue 12, December 2017, Pages 2262-2271, https://doi.org/10.3945/jn.117.252510
  18. Amely M Verreijen, Sjors Verlaan, Mariëlle F Engberink, Sophie Swinkels, Johan de Vogel-van den Bosch, Peter JM Weijs. A high whey protein-, leucine-, and vitamin D-enriched supplement preserves muscle mass during intentional weight loss in obese older adults: a double-blind randomized controlled trial. The American Journal of Clinical Nutrition, Volume 101, Issue 2, February 2015, Pages 279-286, https://doi.org/10.3945/ajcn.114.090290

 

  1. Zheng R, Huang S, Zhu J et al. Leucine attenuates muscle atrophy and autophagosome formation by activating PI3K/AKT/mTOR signaling pathway in rotator cuff tears. Cell Tissue Res 2019. https://doi.org/10.1007/s00441-019-03021-x 

 

  1. Devries MC, Philips SM, Baker SK et al. Leucine, Not Total Protein, Content of a Supplement Is the Primary Determinant of Muscle Protein Anabolic Responses in Healthy Older Women. The Journal of Nutrition, July 1, 2018.

 

  1. Bauer, Jürgen M. et al. Effects of a Vitamin D and Leucine-Enriched Whey Protein Nutritional Supplement on Measures of Sarcopenia in Older Adults, the PROVIDE Study: A Randomized, Double-Blind, Placebo-Controlled Trial. Journal of the American Medical Directors Association, Volume 16, Issue 9, 740-747. September 201

 

  1. Yoshihiro Yoshimura, Takahiro Bise, Fumihiko Takatsuk et al. Effects of a leucine-enriched amino acid supplement on muscle mass,muscle strength, and physical function in post-stroke patients with sarcopenia: A randomized controlled trial. February 2019, Nutrition. https://www.sciencedirect.com/science/article/pii/S089990071830594X?via%3Dihub

 

  1. N Yoshii at al. Effect of Mixed Meal and Leucine Intake on Plasma Amino Acid Concentrations in Young Men. Nutrients, October 2018, 10(10), 1543; https://doi.org/10.3390/nu10101543Amely M Verreijen, Sjors Verlaan, Mariëlle F Engberink, Sophie Swinkels, Johan de Vogel-van den Bosch,

.

  1. Thomas I Gee, Thomas J Woolrich, Mark F Smith. Effectiveness of Whey Protein Hydrolysate and Milk-Based Formulated Drinks on Recovery of Strength and Power Following Acute Resistance Exercise. (August 2019) Journal of Human Kinetics, volume 68/2019, 193-200 DOI: 10.2478/hukin-2019-0066 19
  2. Wilkinson DJ et al. Effects of leucine and its metabolite beta-hydroxy-beta-methylbutyrate on human skeletal muscle protein metabolism. J Physiol 2013,591,2911-2923.

 

  1. Wolfe R. Branched-chain amino acids and muscle protein synthesis in humans: myth or reality? Journal of the International Society of Sports Nutrition, volume 14, Article number: 30 (August 22, 2017)