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science nutrition <strong>blog</strong>

By Robert Schinetsky

 

We’ve discussed at great length (and on many occasions) the power of dopamine. It plays a vital role in motor control, feelings of reward, mood, motivation, and decision-making.

A new animal study recently published in Nature found yet another benefit to this almighty neurotransmitter![1]

Researchers learned that dopamine can control the encoding of cue–reward association rules in the lateral entorhinal cortex (LEC). Additionally, inhibition of LEC dopamine signals disrupted the associative encoding of fan cells and impaired learning performance. From this, researchers concluded that dopamine facilitates the incorporation of new memories.[1]

Basically, in addition to all the better-known roles of dopamine in the body, this new research highlights its role in memory formation!

Dopamine 101

For those of you who may be visiting the AML blog for the first time, or those who may not be as well-versed in the different neurotransmitters of the body, heres a brief recap of dopamine.

Dopamine is one the bodys most important neurotransmitters -- chemicals in the brain that send signals between nerve cells. It affects numerous aspects of daily life, including:

  • Mood
  • Motivation
  • Alertness
  • Energy
  • Athletic performance
  • Libido
  • Mental acuity
  • Decision-making
  • Creativity
  • Overall vitality

 

Quite simply, dopamine makes us feel good, gives us the desire to continue to achieve new goals, and helps us perform better both mentally and physically.

For these reasons (and many more), it’s only natural to want to chase the dopamine “high” and find ways to continue to experience greater surges of dopamine with higher frequency.

This can often lead individuals to adopt less-than-healthy habits and/or experiment with substances that have deleterious effects. One such way to counter this constant quest for more dopamine is to try a “dopamine fast” whereby you abstain from anything stimulating or tantalizing (e.g. alcohol, gambling, social media, sex, drugs...and rock & roll) for at least 24 hours. In some extreme cases, individuals will even stop talking to other people!

There is much truth to the idea that modern society is over-stimulated with a constant barrage of beeps, whistles, bonks, alerts, dings, IMs, DMs, texts, tweets, emails, etc. This is all in addition to the various other avenues by which individuals seek out their fix” for dopamine (e.g. drugs, pornography, alcohol, etc.).

The issue with each and every one of these things is that they do NOT replenish the precursors (“building blocks”) of dopamine in the body. Moreover, a dopamine “fast” doesn’t really lower dopamine levels...sure you might not be overstimulating yourself with all manner of content and/or substances, but your body still needs dopamine to carry out essential daily functions -- decision-making, motor control, memory, etc.

In reality, these dopamine fasts are a fancy way of saying that youre unplugging from tech, de-stressing, and removing clutter from your lifestyle. In a sense, youre slowing things down and getting off of a proverbial hamster wheel for a brief amount of time.

We wont dispute the benefits of taking time away from technology and all the other dopamine-spiking practices, but its also important to give the body what it needs to support and replenish dopamine.

That’s precisely why we’ve created a line of supplements centered around dopamine, including DopaRush Cocktail and DopaRush Shots.

These products are a natural means to replenish the substrates the body needs to produce and maintain sufficient levels of dopamine for optimal performance, creativity, motivation, and focus.

Whats in DopaRush?

L-Tyrosine + Velvet Bean

Dopa Rush™ supplies 2,000 milligrams of L-Tyrosine -- the amino acid the body uses to produce dopamine. Moreover, research has shown that L-tyrosine supplementation may enhance creative thinking, improve the capacity to perform convergent thinking, and boost memory. The same 2,000mg dose is also noted to confer anti-stress benefits, and it may enhance cognitive performance, particularly during acute stressful or cognitively demanding scenarios (which can cause temporary depletions of dopamine).[2,3]

Dopa Rush™ also contains 100 mg of Mucuna pruriens seed (velvet bean) extract, providing the dopamine precursor L-dopa.

This combo provides a 1-2 precursor punch for dopamine production in the body.

But, thats not all…

Folic Acid

In addition to the “heavy hitters” that support dopamine production in the body, there are also other “supporting” cast members that may not get the attention, but play just as important of a role.

Of particular note is folic acid, a highly bioavailable form of vitamin B9.

Folic acid supports dopamine production due to the fact that it’s required for the synthesis of an important cofactor needed for the synthesis of dopamine -- BH4.[4]

Research has noted that low folic acid levels are associated with reduced dopamine levels[5], which themselves are associated with depression.

By providing not only the substrates to fuel dopamine production (L-tyrosine + velvet bean extract) but the key cofactors that facilitate its production, Dopa Rush provides a more complete solution to naturally raising dopamine levels than other products on the market.

Takeaway

Dopa Rush™ is the most potent dopamine-maximizing supplement on the market.

Available in both powder and on-the-go liquid shots, Dopa Rush™ is a dopamine MAXIMIZERthat uses a scientifically-backed formula to increase mental energy, alertness, motivation, focus, and clarity without the jitters, crash, or edgy” feelings of other supplements.

Dopa Rush™ is designed for students, athletes and motivated professionals seeking an edge in class, on the field, at the gym, or in the office.

For added energy, DopaRush also supplies caffeine and Garcinol, which serve to stimulate the release of dopamine and prolong its effects, resulting in greater energy, mood, motivation and focus.

Dopa Rush utilizes a holistic approach to maximizing dopamine production in the body, offering individuals the best way to perform at a higher level each and every day. 

 

©Published by from Advanced Research Media, Inc. 2021
©
Reprinted with permission from Advanced Research Media, Inc.

† These statements have not been evaluated by the Food and Drug Administration.
These statements are not intended to diagnose, treat, cure or prevent any disease.

References

  1. Lee, J.Y., Jun, H., Soma, S. et al. Dopamine facilitates associative memory encoding in the entorhinal cortex. Nature (2021). https://doi.org/10.1038/s41586-021-03948-8
  2. Steenbergen, L., Sellaro, R., Hommel, B., & Colzato, L. S. (2015). Tyrosine promotes cognitive flexibility: evidence from proactive vs. reactive control during task switching performance. Neuropsychologia, 69, 50–55. https://doi.org/10.1016/j.neuropsychologia.2015.01.022
  3. Jongkees, B. J., Hommel, B., Kuhn, S., & Colzato, L. S. (2015). Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands--A review. Journal of Psychiatric Research, 70, 50–57. https://doi.org/10.1016/j.jpsychires.2015.08.014
  4. Homma, D., Katoh, S., Tokuoka, H., & Ichinose, H. (2013). The role of tetrahydrobiopterin and catecholamines in the developmental regulation of tyrosine hydroxylase level in the brain. Journal of Neurochemistry, 126(1), 70–81. https://doi.org/10.1111/jnc.12287
Surtees R, Heales S, Bowron A. Association of cerebrospinal fluid deficiency of 5-methyltetrahydrofolate, but not S-adenosylmethionine, with reduced concentrations of the acid metabolites of 5-hydroxytryptamine and dopamine. Clin Sci 1994;86:697-70