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Restricting food intake to specific times during the day prevented weight gain in mice— according to researchers from the Salk Institute for Biological Studies in La Jolla, California. The animals were fed diets high in fructose, fat or both, all of which contained the same number of calories. Some animals were allowed to eat throughout the day, while others were restricted to feeding either nine, 12 or 15 hours per day. Weight gain was smallest for animals eating only nine hours per day and greatest in animals that ate whenever they wanted. The animals on restricted feeding schedules showed better blood sugar regulation. The composition of the diet did not affect the results. An example in humans might be to not eat anything between 5:00 p.m. and the next morning. Time-restricted feeding might be a relatively painless way to lose weight and promote metabolic health.


(Cell, 20: 991-1005, 2015)