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Ursolic acid is a chemical found in apples, basil, cranberries, peppermint, oregano and prunes. It is used in a variety of cosmetic products and can inhibit the growth of some types of cancer cells. A Korean study found that ursolic acid supplements combined with weight training increased strength and muscle mass more than weight training alone. The supplement appeared to work by increasing levels of irisin in blood. Studies have shown that irisin also makes fat cells more thermogenic (calorie burning). It is found in Advanced Molecular Labs’ (AML) Thermo Heat Ursolic Acid and has recently been shown to increase brown adipose tissue (BAT) or brown fat. BAT normally generates body heat by vigorously burning body fat by a process known as non-shivering thermogenesis. The ability to burn fat with BAT represents a promising way to improve fat loss.


(Korean Journal Physiological Pharmacology, 18: 441-446, 2014)