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Wakame (brown) seaweed contains a chemical called fucoxanthin (FX) that inhibits fat cell growth and promotes fat release. A review of literature by scientists from the Ukraine and Korea noted that most studies on FX have examined its effect on rats and mice. To date, no large-scale studies have been done in humans. Animal studies have shown that FX reduces total body fat and abdominal fat, promotes blood sugar control, prevents fat accumulation in the liver and improves the blood fat profile. Some studies have found that FX increases blood fat activation and increases energy expenditure. Brown seaweed is a natural product with no known toxic effects. (Nutrition, Metabolism & Cardiovascular Diseases, published online June 3, 2015)