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science nutrition blog

science nutrition <strong>blog</strong>

 By Steve Blechman


AML ™ THERMO HEAT® FAT BURNING PROTEIN† is an advanced scientifically designed protein and amino acid drink. I formulated and developed this exciting, revolutionary product based on the latest cutting-edge scientific research! As part of a calorie-restricted diet and exercise (aerobic and resistance training) program, it can help enhance fat loss and preserve lean body mass when following a low-calorie, low-carbohydrate or ketogenic diet. A healthy weight loss is one that enhances the reduction of body fat and preserves lean body mass while dieting.†

AML™ THERMO HEAT® FAT BURNING PROTEIN† is very low in carbohydrates and calories! It contains high-quality whey protein isolate of the highest biological value (no lower-quality hydrolyzed collagen protein is present), enriched with the amino acid L-leucine. Research has shown that vitamin D-3 is the most active form of vitamin D and can potentiate protein synthesis and the muscle-enhancing effects of leucine; and is added to help boost the lean body mass effect of leucine. Also, recent research has shown that vitamin D supplements may enhance fat loss and improve waist-hip ratio, fasting blood glucose in vitamin D-deficient individuals. Leucine-enriched amino acid supplements can help preserve lean muscle mass during dieting. Research has shown that taking 6.25g of whey protein with a high dose of leucine (5g) can enhance protein synthesis at the same rate as four times as much whey protein (25g)! Leucine is the key anabolic trigger of muscle protein synthesis. Increases in muscle protein synthesis are dependent on leucine concentration. 5 grams of leucine can increase the anabolic effects of protein synthesis by eating less protein, which is ideal on a ketogenic diet. Older adults (people over 40) show a blunted muscle protein synthesis (MPS) and anabolic resistance compared to younger adults. Recent research has suggested that the anabolic resistance can be overcome by consuming greater quantities of leucine. In a recent study, published in the Journal of Nutrition on July 1, 2018, it is confirmed that leucine and not total protein content of a “… supplement is the primary determinant of muscle protein anabolic responses in healthy older women.” Lower-protein supplements with added leucine may represent an advantageous approach in older adults to maintain skeletal muscle anabolic sensitivity and attenuate muscle loss. Research has shown that leucine can enhance fat loss and promote weight loss during energy restriction. Leucine improves mitochondrial biogenesis and fatty acid oxidation and fat burning through SIRT-1 and AMPK-dependent pathways. AMPK (5 adenosine-monophosphate-activated protein kinase) regulates energy expenditure by modulating NAD metabolism and SIRT-1 activity. Leucine also increases glucagon-like peptide-1 (GLP-1), often referred to as the “satiety hormone.”†

AML™ THERMO HEAT® FAT BURNING PROTEIN† contains a thermogenic blend of whey protein and leucine. It also contains nitric oxide activators (L-citrulline, grape skin polyphenols and folic acid). Nitric oxide has been shown to enhance brown adipose tissue (BAT) activity and thermogenesis. L-citrulline and L-arginine enhances nitric oxide and brown fat activity and thermogenesis. The more brown fat you have, the more calories you burn. Citrulline is a more effective supplement than arginine for promoting intracellular nitric oxide! Citrulline has also been shown to reduce blood sugar production in the liver and stimulate abdominal fat loss. Citrulline has also been shown to increase levels of hormone-sensitive lipase by 150%, further enhancing fat burning. Citrulline supplementation may also facilitate the detoxification of ammonia via the urea cycle in the liver. As your body breaks down protein for energy, it produces ammonia, which can cause fatigue. Research has shown that reduced calorie and carbohydrate diets can increase blood ammonia levels especially when combined with high-intensity exercise. A most recent study in BMC Research Notes showed that 12 weeks of supplementation with two grams per day of citrulline lowered inflammation and inflammatory markers (c-reactive protein and tumor necrosis factor) in patients with non-alcoholic fatty liver disease (NAFLD). Many people with NAFLD don’t drink much alcohol. The most common form of liver disease in the United States is NAFLD, which affects 80 to 100 million people! Risk factors include being overweight, abdominal obesity, high cholesterol, and LDL (bad) cholesterol, high triglycerides and pre-diabetes, or type 2 diabetes. NAFLD can progress to a more serious disease like non-alcoholic steatohepatitis (NASH) and cause serious liver damage, inflammation, liver cancer, cirrhosis, and liver failure resulting in liver transplant. Not only is citrulline supplementation good for metabolic health, but grape skin extract rich in polyphenols has also been shown to increase nitric oxide production. Polyphenols are being studied on their role in fat metabolism and obesity management. Folic acid also boosts nitric oxide availability, by increasing BH4 and decreasing homocysteine levels. Research has shown that folic acid can lower homocysteine levels, increase insulin sensitivity and lower fasting insulin levels in type 2 diabetes. Medium-chain triglycerides (MCTs), grains of paradise (40mg - standardized for 12% paradol, a clinically effective dose) and BioPerine® black pepper fruit extract are all included for further activation of brown adipose tissue (BAT) and thermogenesis. Grains of paradise, a spice containing 6-paradol, like chili peppers containing capsaicin, activate BAT, increase whole-body energy expenditure, and decrease visceral fat (deep abdominal fat) in humans. Alluose is added as a natural, low-calorie, fat-burning, thermogenic sweetener. It is approved for low-sugar/low-carb or ketogenic diets. Alluose does not impact blood sugar or insulin levels. A recent study in the March 2019 issue of the Journal of Circulation found that the more sugar beverages people drank including soft drinks, fruit drinks and energy drinks, the greater the risk of death! Diet drinks that were sweetened with sugar substitute were not linked with an increased risk of death during this study period. Potassium and magnesium citrate are added as important electrolytes and acid buffers (alkalinizers) when following low-carb and ketogenic diets. Low-grade chronic acidosis (which can increase muscle protein breakdown and bone loss), dehydration, electrolyte (mineral) loss and kidney stones are more prevalent in those people following a low-carb or ketogenic diets. Potassium citrate may help preserve lean body mass by reducing blood acidity in those following a low-carb ketogenic diet. Also, recent research has shown that potassium citrate can help prevent kidney stones in those people following a low-carb or ketogenic diet! Also, a recent study presented March 16th and March 17, 2019 in New Orleans at the Annual American College of Cardiology 68th Annual Scientific Sessions showed that low-carb diets can raise the risk of heart rhythm disorders like atrial fibrillation, in susceptible individuals. The loss of potassium and depletion of other electrolytes such as magnesium has an enormous effect on the functioning of the heart. Low serum potassium and magnesium is associated with higher risk of atrial fibrillation. There may be an increased risk of arrhythmia if your serum potassium levels are low, which may occur on some very low calorie, low-carb and ketogenic diets. AML™ THERMO HEAT® FAT BURNING PROTEIN contains a full 750mg of potassium and 100mg of magnesium in each serving. †

AML™ THERMO HEAT® FAT BURNING PROTEIN† does not contain pure ketone supplements such as beta-hydroxybutyrate (BHB). Ketone supplements in the form of BHB salts and ketone esters only provide a temporary increase in blood ketone levels. Ingesting exogenous ketones may briefly interrupt your body’s natural production of ketones. BHB salts do not stimulate ketogenesis. Ketone supplementation reduces lipolysis and free fatty acids availability and may inhibit the body’s natural ability to burn its own body fat for fuel. A most recent study has shown that feeding ketone BHB supplements in healthy humans may have an undesirable effect by activating the innate immune response and increase inflammation. This randomized double-blind placebo-controlled experiment is very concerning (March 25, 2019, Nutrition & Food Research.) Be cautious of ketone supplements such as calcium BHB and loading up on calcium! Calcium BHB supplements are high in calcium. High blood calcium (hypercalcemia) may increase the risk of kidney stones in susceptible individuals. People on ketogenic diets have been known to be at greater risk of kidney stones. Medium-chain triglycerides (MCTs) naturally increase the production of ketones in the liver and stimulate ketogenesis. Research has shown that MCT supplements do not cause feedback inhibition or reduce ketone production. MCTs also help reduce appetite and food intake, enhance fatty acid oxidation, fat burning, energy expenditure, and thermogenesis and reduce body fat accumulation in humans. Research has shown that MCTs (a saturated fat) also does not have a negative effect on blood lipids in humans. MCTs significantly increase “good” HDL cholesterol with no effect on triglycerides or “bad” LDL cholesterol. Don’t confuse MCTs with coconut oil. Claims that the majority of fat in coconut oil are MCTs is untrue. The thermogenic/weight-loss research has been done on pure MCT oil, not coconut oil. It’s inaccurate to apply the research on pure 100% MCT oil to coconut oil, which only has 13% of MCTs.†

AML™ THERMO HEAT® FAT BURNING PROTEIN† can be taken after a workout or as a meal replacement. Recent research has shown that leucine intake from a supplement may be better for muscle protein synthesis than leucine from a meal! It can also be taken 30 minutes before a meal. Research has shown that low-dose whey protein taken before a meal is effective in reducing glycemia (elevated blood sugar) after a meal. People consuming high-dose whey supplements on a ketogenic diet can potentially throw their body out of ketosis. People following a ketogenic diet try to keep dietary protein levels lower to maintain ketosis. Whey protein is rich in branched-chain amino acids (leucine, isoleucine, and valine.) Leucine is a solely ketogenic amino acid; it is not glucogenic! Isoleucine is ketogenic and glucogenic and valine is 100% glucogenic! Whey protein also contains other glucogenic amino acids which may not be desirable in those people following the ketogenic diet. By keeping the whey protein in the AML™ THERMO HEAT® FAT BURNING PROTEIN low, and boosting the leucine, this will keep isoleucine and valine low – which are both glucogenic amino acids especially, valine. This makes AML™ THERMO HEAT® FAT BURNING PROTEIN more ketogenic than 100% whey protein!

AML™ THERMO HEAT® FAT BURNING PROTEIN is a scientifically designed product for people following very low-carbohydrate or ketogenic diets! Sciencedaily recently reported that, “The often embraced 'cheat day' is a common theme in many diets and the popular ketogenic diet is no exception. But new research from UBC's Okanagan campus says that just one 75-gram dose of glucose -- the equivalent a large bottle of soda or a plate of fries -- while on a high fat, low carbohydrate diet can lead to damaged blood vessels.” This article was supported by a study that was published in the journal Nutrients on February 25, 2019. Sciencedaily also reported that, “Since impaired glucose tolerance and spikes in blood sugar levels are known to be associated with an increased risk in cardiovascular disease, it made sense to look at what was happening in the blood vessels after a sugar hit." AML™ THERMO HEAT® FAT BURNING PROTEIN can also be taken before a cheat meal to lower postprandial glucose and insulin levels! In addition, it can be taken as a low-calorie protein-sparing anabolic snack to help preserve lean body mass during dieting or can be added to a cup of hot coffee.†

For optimum results, take AML™ THERMO HEATTHERMO HEAT® NIGHTTIME, AND THERMO HEAT® MULTI capsules daily as part of a caloric-restrictive diet and exercise (aerobic/resistance training program). There is an overwhelming amount of science and research supporting the Thermo Heat Fat Burning cutting edge, scientifically-based formula. When AML™ THERMO HEAT® FAT BURNING PROTEIN is combined with AML™ THERMO HEAT capsules,® THERMO HEAT® NIGHTTIME, THERMO HEAT® MULTI, THERMO HEAT Mediterranean Low-Carb diet and The THERMO HEAT,® HIIT workout plus, The THERMO HEAT-Total-Body Fat-Incinerating Exercise Plan – it provides a very powerful scientifically documented fat loss and weight management program!!

WARNING: Not recommended for anyone under the age of 18 or if you are pregnant or nursing. Check with your physician if you have a medical condition or before beginning any diet or supplement program.

The book entitled Thermo Heat® Weight Loss Revolution by Michael Rudolph, Ph.D. outlines, in chapter 2, The Thermo Heat HIIT Workout, plus The Thermo Heat Total-Body Fat-Incinerating Exercise Plan. The book also provides a calorie-controlled, low-carb Mediterranean diet, 30-day meal plan and exercise program. It says that you should limit yourself to 100 grams of carbohydrates per day, or less. If you want to follow the ketogenic diet, carbohydrates should be kept at less than 50 grams per day. US News & World Report selected the Mediterranean Diet as the best overall diet for 2019 (US News & World Report; Jan 2nd, 2019). It was also rated the best diet for preventing heart disease and diabetes. These results were based on a panel of 23 experts, and 41 diets based on the scientific literature. A meta-analysis in the British Journal of Nutrition (2013) of 13 randomized controlled trials suggested that very low carbohydrate ketogenic diets lost more weight compared to low fat diets. A recent study published in the British Medical Journal (BMJ, 2018) found that very low-carb diets burn 250mg more calories per day compared to people who consume low-fat-high-carb diets. A study found in the journal Circulation (2017) found that the Mediterranean low-carb diet was significantly superior to a low-fat diet in decreasing fat storage, including visceral (deep abdominal) liver and heart fat. High visceral fat has been shown to increase metabolic syndrome, inflammation, cardiovascular disease and diabetes. Losing deep subcutaneous visceral fat, as well as haptic (liver) fat, was associated with improved insulin sensitivity and improved lipid profile.

The low-carb Mediterranean diet as presented in a study published in the journal Circulation (2017) was found to be more effective than a low-fat diet in eliminating fat storage. Previous studies have shown that a low-carb Mediterranean diet may be an effective alternative to low-fat diets. It has a more favorable effect on lipids (with low-carb diet) and glycemic control (with Mediterranean diet.)

The Thermo Heat® Weight Loss Revolution stresses foods high in monounsaturated and omega-3 polyunsaturated fatty acids. It also recommends thermogenic, brown fat-activating herbs and spices instead of salt to flavor food— such as garlic, onion, mustard and chili pepper (capsaicin) to name a few. Monounsaturated fats are more thermogenic than saturated fats found in high-fat dairy and red meat. Processed food and sugar are off the table! Because of ease of compliance, The Thermo Heat® Weight Loss Revolution Mediterranean diet makes it easy to follow even when dining out. One or two glasses of polyphenol-rich red wine (not white wine, or any other alcoholic beverages) per day can have positive, health benefits on the Mediterranean diet. Studies show that olive oil and certain spices can enhance brown fat and increase thermogenesis. A number of studies have shown that healthy fats from nuts, olive oil and fish, found predominantly in Italian, Greek and Turkish cuisine, have health benefits in the prevention of heart disease, type 2 diabetes and obesity. Fish oil and omega-3 fats can decrease bodyweight gain and fat accumulation by increasing thermogenesis and energy expenditure.

For more authoritative information, see the Thermo Heat® Weight Loss Revolution by Michael J. Rudolph, Ph.D., including the foreword by Daniel L. Friedman, MD and Eugene B. Friedman, MD. You can click the link to order here. The body has two forms of fat white fat and brown fat. Brown fat burns calories. The more brown fat you have, the more calories you burn. The capability of harnessing one’s own brown fat is revolutionary! The ability to get lean by producing extra brown fat and enhancing and activating existing brown fat represent a promising way to burn fat. Several landmark discoveries and approaches to this are being explored at major research centers and universities worldwide, with great excitement. Brown fat research is a hot topic today! The Thermo Heat® Weight Loss Revolution is a groundbreaking, scientific plan based on research involving brown fat (BAT) and offers its readers a brown fat, thermogenic and brown fat-activating diet, nutrition, supplement(s) and exercise program. You can also get a free PDF version here.





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